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Diversity of antigenic mutants of influenza A(H1N1)pdm09 virus escaped from human monoclonal antibodies

Since the 2017 Southern Hemisphere influenza season, the A(H1N1)pdm09-like virus recommended for use in the vaccine was changed because human, but not ferret, sera distinguish A(H1N1)pdm09 viruses isolated after 2013 from the previously circulating strains. An amino acid substitution, lysine to glut...

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Detalles Bibliográficos
Autores principales: Yasuhara, Atsuhiro, Yamayoshi, Seiya, Soni, Priyanka, Takenaga, Toru, Kawakami, Chiharu, Takashita, Emi, Sakai-Tagawa, Yuko, Uraki, Ryuta, Ito, Mutsumi, Iwatsuki-Horimoto, Kiyoko, Sasaki, Tadahiro, Ikuta, Kazuyoshi, Yamada, Shinya, Kawaoka, Yoshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5735164/
https://www.ncbi.nlm.nih.gov/pubmed/29255273
http://dx.doi.org/10.1038/s41598-017-17986-8