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Frataxin‐deficient neurons and mice models of Friedreich ataxia are improved by TAT‐MTScs‐FXN treatment

Friedreich ataxia (FA) is a rare disease caused by deficiency of frataxin, a mitochondrial protein. As there is no cure available for this disease, many strategies have been developed to reduce the deleterious effects of such deficiency. One of these approaches is based on delivering frataxin to the...

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Detalles Bibliográficos
Autores principales: Britti, Elena, Delaspre, Fabien, Feldman, Anat, Osborne, Melissa, Greif, Hagar, Tamarit, Jordi, Ros, Joaquim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783845/
https://www.ncbi.nlm.nih.gov/pubmed/28980774
http://dx.doi.org/10.1111/jcmm.13365