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Mechanisms driving the antibacterial and antibiofilm properties of Hp1404 and its analogue peptides against multidrug-resistant Pseudomonas aeruginosa
Hp1404, identified from the venom of the scorpion Heterometrus petersii, displays antimicrobial activity with cytotoxicity. Several synthetic peptides were designed based on the parent peptide Hp1404 to reduce cytotoxicity and improve activity (deletion of glycine and phenylalanine, substitution wit...
Autores principales: | Kim, Min Kyung, Kang, Hee Kyoung, Ko, Su Jin, Hong, Min Ji, Bang, Jeong Kyu, Seo, Chang Ho, Park, Yoonkyung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789083/ https://www.ncbi.nlm.nih.gov/pubmed/29379033 http://dx.doi.org/10.1038/s41598-018-19434-7 |
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