Cardiovascular adjustments during anticipated postural changes

It is well‐documented that feedforward cardiovascular responses occur at the onset of exercise, but it is unclear if such responses are associated with other types of movements. In this study, we tested the hypothesis that feedforward cardiovascular responses occur when a passive (imposed) 60° head‐...

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Autores principales: Patel, Neesirg M., Baker, Ethan A.G., Wittman, Samuel R., Engstrom, Isaiah C., Bourdages, George H., McCall, Andrew A., Miller, Derek M., Yates, Bill. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789654/
https://www.ncbi.nlm.nih.gov/pubmed/29333722
http://dx.doi.org/10.14814/phy2.13554
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author Patel, Neesirg M.
Baker, Ethan A.G.
Wittman, Samuel R.
Engstrom, Isaiah C.
Bourdages, George H.
McCall, Andrew A.
Miller, Derek M.
Yates, Bill. J.
author_facet Patel, Neesirg M.
Baker, Ethan A.G.
Wittman, Samuel R.
Engstrom, Isaiah C.
Bourdages, George H.
McCall, Andrew A.
Miller, Derek M.
Yates, Bill. J.
author_sort Patel, Neesirg M.
collection PubMed
description It is well‐documented that feedforward cardiovascular responses occur at the onset of exercise, but it is unclear if such responses are associated with other types of movements. In this study, we tested the hypothesis that feedforward cardiovascular responses occur when a passive (imposed) 60° head‐up tilt is anticipated, such that changes in heart rate and carotid artery blood flow (CBF) commence prior to the onset of the rotation. A light cue preceded head‐up tilts by 10 sec, and heart rate and CBF were determined for 5‐sec time periods prior to and during tilts. Even after these stimuli were provided for thousands of trials spanning several months, no systematic changes in CBF and heart rate occurred prior to tilts, and variability in cardiovascular adjustments during tilt remained substantial over time. We also hypothesized that substitution of 20° for 60° tilts in a subset of trials would result in exaggerated cardiovascular responses (as animals expected 60° tilts), which were not observed. These data suggest that cardiovascular adjustments during passive changes in posture are mainly elicited by feedback mechanisms, and that anticipation of passive head‐up tilts does not diminish the likelihood that a decrease in carotid blood flow will occur during the movements.
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spelling pubmed-57896542018-03-15 Cardiovascular adjustments during anticipated postural changes Patel, Neesirg M. Baker, Ethan A.G. Wittman, Samuel R. Engstrom, Isaiah C. Bourdages, George H. McCall, Andrew A. Miller, Derek M. Yates, Bill. J. Physiol Rep Original Research It is well‐documented that feedforward cardiovascular responses occur at the onset of exercise, but it is unclear if such responses are associated with other types of movements. In this study, we tested the hypothesis that feedforward cardiovascular responses occur when a passive (imposed) 60° head‐up tilt is anticipated, such that changes in heart rate and carotid artery blood flow (CBF) commence prior to the onset of the rotation. A light cue preceded head‐up tilts by 10 sec, and heart rate and CBF were determined for 5‐sec time periods prior to and during tilts. Even after these stimuli were provided for thousands of trials spanning several months, no systematic changes in CBF and heart rate occurred prior to tilts, and variability in cardiovascular adjustments during tilt remained substantial over time. We also hypothesized that substitution of 20° for 60° tilts in a subset of trials would result in exaggerated cardiovascular responses (as animals expected 60° tilts), which were not observed. These data suggest that cardiovascular adjustments during passive changes in posture are mainly elicited by feedback mechanisms, and that anticipation of passive head‐up tilts does not diminish the likelihood that a decrease in carotid blood flow will occur during the movements. John Wiley and Sons Inc. 2018-01-15 /pmc/articles/PMC5789654/ /pubmed/29333722 http://dx.doi.org/10.14814/phy2.13554 Text en © 2018 The Authors. Physiological Reports published by Wiley Periodicals, Inc. on behalf of The Physiological Society and the American Physiological Society This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Research
Patel, Neesirg M.
Baker, Ethan A.G.
Wittman, Samuel R.
Engstrom, Isaiah C.
Bourdages, George H.
McCall, Andrew A.
Miller, Derek M.
Yates, Bill. J.
Cardiovascular adjustments during anticipated postural changes
title Cardiovascular adjustments during anticipated postural changes
title_full Cardiovascular adjustments during anticipated postural changes
title_fullStr Cardiovascular adjustments during anticipated postural changes
title_full_unstemmed Cardiovascular adjustments during anticipated postural changes
title_short Cardiovascular adjustments during anticipated postural changes
title_sort cardiovascular adjustments during anticipated postural changes
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789654/
https://www.ncbi.nlm.nih.gov/pubmed/29333722
http://dx.doi.org/10.14814/phy2.13554
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