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Engineered exosome-mediated delivery of functionally active miR-26a and its enhanced suppression effect in HepG2 cells

INTRODUCTION: Exosomes are closed-membrane nanovesicles that are secreted by a variety of cells and exist in most body fluids. Recent studies have demonstrated the potential of exosomes as natural vehicles that target delivery of functional small RNA and chemotherapeutics to diseased cells. METHODS:...

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Detalles Bibliográficos
Autores principales: Liang, Gaofeng, Kan, Shu, Zhu, Yanliang, Feng, Shuying, Feng, Wenpo, Gao, Shegan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796471/
https://www.ncbi.nlm.nih.gov/pubmed/29430178
http://dx.doi.org/10.2147/IJN.S154458