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Phase I Randomized Study of a Tetravalent Dengue Purified Inactivated Vaccine in Healthy Adults from Puerto Rico
The safety and immunogenicity of four adjuvanted formulations of an investigational tetravalent dengue purified inactivated vaccine (DPIV) were evaluated in a predominantly dengue-primed population in Puerto Rico. In this placebo-controlled, randomized, observer-blind, phase I trial, 100 healthy adu...
Autores principales: | Diaz, Clemente, Lin, Leyi, Martinez, Luis J., Eckels, Kenneth H., Campos, Maribel, Jarman, Richard G., De La Barrera, Rafael, Lepine, Edith, Toussaint, Jean-François, Febo, Irma, Innis, Bruce L., Thomas, Stephen J., Schmidt, Alexander C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society of Tropical Medicine and Hygiene
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953365/ https://www.ncbi.nlm.nih.gov/pubmed/29512481 http://dx.doi.org/10.4269/ajtmh.17-0627 |
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