Enhanced ZnR/GPR39 Activity in Breast Cancer, an Alternative Trigger of Signaling Leading to Cell Growth

Acquired resistance to the estrogen receptor (ER) antagonist tamoxifen, is a major obstacle in treatment of breast cancer. Changes in Zn(2+) accumulation and distribution are associated with tamoxifen-resistance and breast cancer progression. The Zn(2+)-sensing G-protein coupled receptor, ZnR/GPR39,...

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Detalles Bibliográficos
Autores principales: Ventura-Bixenshpaner, Hila, Asraf, Hila, Chakraborty, Moumita, Elkabets, Moshe, Sekler, Israel, Taylor, Kathryn M., Hershfinkel, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5970167/
https://www.ncbi.nlm.nih.gov/pubmed/29802348
http://dx.doi.org/10.1038/s41598-018-26459-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5970167/
https://www.ncbi.nlm.nih.gov/pubmed/29802348
http://dx.doi.org/10.1038/s41598-018-26459-5

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