MicroRNA-29b-2-5p inhibits cell proliferation by directly targeting Cbl-b in pancreatic ductal adenocarcinoma

BACKGROUND: MicroRNAs can be used in the prognosis of malignancies; however, their regulatory mechanisms are unknown, especially in pancreatic ductal adenocarcinoma (PDAC). METHODS: In 120 PDAC specimens, miRNA levels were assessed by quantitative real time polymerase chain reaction (qRT-PCR). Then,...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Ce, Dong, Qian, Che, Xiaofang, Xu, Ling, Li, Zhi, Fan, Yibo, Hou, Kezuo, Wang, Shuo, Qu, Jinglei, Xu, Lu, Wen, Ti, Yang, Xianghong, Qu, Xiujuan, Liu, Yunpeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019739/
https://www.ncbi.nlm.nih.gov/pubmed/29940895
http://dx.doi.org/10.1186/s12885-018-4526-z