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Coregulation of alternative splicing by hnRNPM and ESRP1 during EMT

The epithelial–mesenchymal transition (EMT) is a fundamental developmental process that is abnormally activated in cancer metastasis. Dynamic changes in alternative splicing occur during EMT. ESRP1 and hnRNPM are splicing regulators that promote an epithelial splicing program and a mesenchymal splic...

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Detalles Bibliográficos
Autores principales: Harvey, Samuel E., Xu, Yilin, Lin, Xiaodan, Gao, Xin D., Qiu, Yushan, Ahn, Jaegyoon, Xiao, Xinshu, Cheng, Chonghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140460/
https://www.ncbi.nlm.nih.gov/pubmed/30042172
http://dx.doi.org/10.1261/rna.066712.118