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Cytoplasmic FOXO1 identifies a novel disease-activity associated B cell phenotype in SLE

Systemic lupus erythematosus (SLE) is a manifestation of hyperactivated lymphocytes and results, in part, from the loss of normal tolerance checkpoints. FOXO1 is a transcription factor involved at critical early and late B cell development checkpoints; however, its role in regulating peripheral B ce...

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Detalles Bibliográficos
Autores principales: Hritzo Ahye, Molly K, Golding, Amit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203050/
https://www.ncbi.nlm.nih.gov/pubmed/30397498
http://dx.doi.org/10.1136/lupus-2018-000296