Direct pathway cloning of the sodorifen biosynthetic gene cluster and recombinant generation of its product in E. coli

BACKGROUND: Serratia plymuthica WS3236 was selected for whole genome sequencing based on preliminary genetic and chemical screening indicating the presence of multiple natural product pathways. This led to the identification of a putative sodorifen biosynthetic gene cluster (BGC). The natural produc...

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Detalles Bibliográficos
Autores principales: Duell, Elke R., D’Agostino, Paul M., Shapiro, Nicole, Woyke, Tanja, Fuchs, Thilo M., Gulder, Tobias A. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366047/
https://www.ncbi.nlm.nih.gov/pubmed/30732610
http://dx.doi.org/10.1186/s12934-019-1080-6