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Cancer-associated fibroblasts enhance tumor-associated macrophages enrichment and suppress NK cells function in colorectal cancer

Cancer-associated fibroblasts (CAFs) and tumor-associated macrophages (TAMs) are important components of the tumor microenvironment, which have been reported to localize in colorectal carcinomas where they promote tumor progression. One of the crucial effects they exerted is immune-suppression, whic...

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Detalles Bibliográficos
Autores principales: Zhang, Rongsheng, Qi, Fan, Zhao, Fei, Li, Geng, Shao, Shengli, Zhang, Xiaochao, Yuan, Lifei, Feng, Yongdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426970/
https://www.ncbi.nlm.nih.gov/pubmed/30894509
http://dx.doi.org/10.1038/s41419-019-1435-2