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Determination of local chromatin interactions using a combined CRISPR and peroxidase APEX2 system
The architecture and function of chromatin are largely regulated by local interacting molecules, such as transcription factors and noncoding RNAs. However, our understanding of these regulatory molecules at a given locus is limited because of technical difficulties. Here, we describe the use of Clus...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511869/ https://www.ncbi.nlm.nih.gov/pubmed/30805613 http://dx.doi.org/10.1093/nar/gkz134 |