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Determination of local chromatin interactions using a combined CRISPR and peroxidase APEX2 system

The architecture and function of chromatin are largely regulated by local interacting molecules, such as transcription factors and noncoding RNAs. However, our understanding of these regulatory molecules at a given locus is limited because of technical difficulties. Here, we describe the use of Clus...

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Detalles Bibliográficos
Autores principales: Qiu, Wenqing, Xu, Zhijiao, Zhang, Min, Zhang, Dandan, Fan, Hui, Li, Taotao, Wang, Qianfeng, Liu, Peiru, Zhu, Zaihua, Du, Duo, Tan, Minjia, Wen, Bo, Liu, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511869/
https://www.ncbi.nlm.nih.gov/pubmed/30805613
http://dx.doi.org/10.1093/nar/gkz134