Caspase-mediated cleavage of murine norovirus NS1/2 potentiates apoptosis and is required for persistent infection of intestinal epithelial cells

Human norovirus (HNoV) is the leading cause of acute gastroenteritis and is spread by fecal shedding that can often persist for weeks to months after the resolution of symptoms. Elimination of persistent viral reservoirs has the potential to prevent outbreaks. Similar to HNoV, murine norovirus (MNV)...

Descripción completa

Detalles Bibliográficos
Autores principales: Robinson, Bridget A., Van Winkle, Jacob A., McCune, Broc T., Peters, A. Mack, Nice, Timothy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6675124/
https://www.ncbi.nlm.nih.gov/pubmed/31329638
http://dx.doi.org/10.1371/journal.ppat.1007940

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6675124/
https://www.ncbi.nlm.nih.gov/pubmed/31329638
http://dx.doi.org/10.1371/journal.ppat.1007940

Ejemplares similares