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Methylation Dynamics of RASSF1A and Its Impact on Cancer

5-methyl cytosine (5mC) is a key epigenetic mark entwined with gene expression and the specification of cellular phenotypes. Its distribution around gene promoters sets a barrier for transcriptional enhancers or inhibitor proteins binding to their target sequences. As a result, an additional level o...

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Detalles Bibliográficos
Autores principales: Malpeli, Giorgio, Innamorati, Giulio, Decimo, Ilaria, Bencivenga, Maria, Nwabo Kamdje, Armel Herve, Perris, Roberto, Bassi, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678546/
https://www.ncbi.nlm.nih.gov/pubmed/31323949
http://dx.doi.org/10.3390/cancers11070959