Impact of natural light exposure on delirium burden in adult patients receiving invasive mechanical ventilation in the ICU: a prospective study

OBJECTIVE: To determine whether potential exposure to natural light via windows is associated with reduced delirium burden in critically ill patients admitted to the ICU in a single room. DESIGN: Prospective single-center study. SETTING: Medical ICU of a university hospital, Paris, France. PATIENTS:...

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Autores principales: Smonig, Roland, Magalhaes, Eric, Bouadma, Lila, Andremont, Olivier, de Montmollin, Etienne, Essardy, Fatiah, Mourvillier, Bruno, Lebut, Jordane, Dupuis, Claire, Neuville, Mathilde, Lermuzeaux, Mathilde, Timsit, Jean-François, Sonneville, Romain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797676/
https://www.ncbi.nlm.nih.gov/pubmed/31624936
http://dx.doi.org/10.1186/s13613-019-0592-x
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author Smonig, Roland
Magalhaes, Eric
Bouadma, Lila
Andremont, Olivier
de Montmollin, Etienne
Essardy, Fatiah
Mourvillier, Bruno
Lebut, Jordane
Dupuis, Claire
Neuville, Mathilde
Lermuzeaux, Mathilde
Timsit, Jean-François
Sonneville, Romain
author_facet Smonig, Roland
Magalhaes, Eric
Bouadma, Lila
Andremont, Olivier
de Montmollin, Etienne
Essardy, Fatiah
Mourvillier, Bruno
Lebut, Jordane
Dupuis, Claire
Neuville, Mathilde
Lermuzeaux, Mathilde
Timsit, Jean-François
Sonneville, Romain
author_sort Smonig, Roland
collection PubMed
description OBJECTIVE: To determine whether potential exposure to natural light via windows is associated with reduced delirium burden in critically ill patients admitted to the ICU in a single room. DESIGN: Prospective single-center study. SETTING: Medical ICU of a university hospital, Paris, France. PATIENTS: Adult patients receiving invasive mechanical ventilation. METHODS: Consecutive patients admitted to a single room with (LIGHT group) or without (DARK group) exposure to natural light via windows were evaluated for delirium. The primary endpoint was the incidence of delirium. Main secondary endpoints included incidence of severe agitation intervened with antipsychotics and incidence of hallucinations. RESULTS: A total of 195 patients were included (LIGHT group: n = 110; DARK group: n = 85). The incidence of delirium was similar in the LIGHT group and the DARK group (64% vs. 71%; relative risk (RR) 0.89, 95% CI 0.73–1.09). Compared with the DARK group, patients from the LIGHT group were less likely to be intervened with antipsychotics for agitation episodes (13% vs. 25%; RR 0.52, 95% CI 0.27–0.98) and had less frequent hallucinations (11% vs. 22%; RR 0.49, 95% CI 0.24–0.98). In multivariate logistic regression analysis, natural light exposure was independently associated with a reduced risk of agitation episodes intervened with antipsychotics (adjusted odds ratio = 0.39; 95% CI 0.17–0.88). CONCLUSION: Admission to a single room with potential exposure to natural light via windows was not associated with reduced delirium burden, as compared to admission to a single room without windows. However, natural light exposure was associated with a reduced risk of agitation episodes and hallucinations.
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spelling pubmed-67976762019-10-24 Impact of natural light exposure on delirium burden in adult patients receiving invasive mechanical ventilation in the ICU: a prospective study Smonig, Roland Magalhaes, Eric Bouadma, Lila Andremont, Olivier de Montmollin, Etienne Essardy, Fatiah Mourvillier, Bruno Lebut, Jordane Dupuis, Claire Neuville, Mathilde Lermuzeaux, Mathilde Timsit, Jean-François Sonneville, Romain Ann Intensive Care Research OBJECTIVE: To determine whether potential exposure to natural light via windows is associated with reduced delirium burden in critically ill patients admitted to the ICU in a single room. DESIGN: Prospective single-center study. SETTING: Medical ICU of a university hospital, Paris, France. PATIENTS: Adult patients receiving invasive mechanical ventilation. METHODS: Consecutive patients admitted to a single room with (LIGHT group) or without (DARK group) exposure to natural light via windows were evaluated for delirium. The primary endpoint was the incidence of delirium. Main secondary endpoints included incidence of severe agitation intervened with antipsychotics and incidence of hallucinations. RESULTS: A total of 195 patients were included (LIGHT group: n = 110; DARK group: n = 85). The incidence of delirium was similar in the LIGHT group and the DARK group (64% vs. 71%; relative risk (RR) 0.89, 95% CI 0.73–1.09). Compared with the DARK group, patients from the LIGHT group were less likely to be intervened with antipsychotics for agitation episodes (13% vs. 25%; RR 0.52, 95% CI 0.27–0.98) and had less frequent hallucinations (11% vs. 22%; RR 0.49, 95% CI 0.24–0.98). In multivariate logistic regression analysis, natural light exposure was independently associated with a reduced risk of agitation episodes intervened with antipsychotics (adjusted odds ratio = 0.39; 95% CI 0.17–0.88). CONCLUSION: Admission to a single room with potential exposure to natural light via windows was not associated with reduced delirium burden, as compared to admission to a single room without windows. However, natural light exposure was associated with a reduced risk of agitation episodes and hallucinations. Springer International Publishing 2019-10-17 /pmc/articles/PMC6797676/ /pubmed/31624936 http://dx.doi.org/10.1186/s13613-019-0592-x Text en © The Author(s) 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Research
Smonig, Roland
Magalhaes, Eric
Bouadma, Lila
Andremont, Olivier
de Montmollin, Etienne
Essardy, Fatiah
Mourvillier, Bruno
Lebut, Jordane
Dupuis, Claire
Neuville, Mathilde
Lermuzeaux, Mathilde
Timsit, Jean-François
Sonneville, Romain
Impact of natural light exposure on delirium burden in adult patients receiving invasive mechanical ventilation in the ICU: a prospective study
title Impact of natural light exposure on delirium burden in adult patients receiving invasive mechanical ventilation in the ICU: a prospective study
title_full Impact of natural light exposure on delirium burden in adult patients receiving invasive mechanical ventilation in the ICU: a prospective study
title_fullStr Impact of natural light exposure on delirium burden in adult patients receiving invasive mechanical ventilation in the ICU: a prospective study
title_full_unstemmed Impact of natural light exposure on delirium burden in adult patients receiving invasive mechanical ventilation in the ICU: a prospective study
title_short Impact of natural light exposure on delirium burden in adult patients receiving invasive mechanical ventilation in the ICU: a prospective study
title_sort impact of natural light exposure on delirium burden in adult patients receiving invasive mechanical ventilation in the icu: a prospective study
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797676/
https://www.ncbi.nlm.nih.gov/pubmed/31624936
http://dx.doi.org/10.1186/s13613-019-0592-x
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