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Antigen‐specific CD8 T cells in cell cycle circulate in the blood after vaccination

Although clonal expansion is a hallmark of adaptive immunity, the location(s) where antigen‐responding T cells enter cell cycle and complete it have been poorly explored. This lack of knowledge stems partially from the limited experimental approaches available. By using Ki67 plus DNA staining and a...

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Detalles Bibliográficos
Autores principales: Simonetti, Sonia, Natalini, Ambra, Folgori, Antonella, Capone, Stefania, Nicosia, Alfredo, Santoni, Angela, Di Rosa, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6850756/
https://www.ncbi.nlm.nih.gov/pubmed/30488973
http://dx.doi.org/10.1111/sji.12735