Mechanism of synergistic actin filament pointed end depolymerization by cyclase-associated protein and cofilin

The ability of cells to generate forces through actin filament turnover was an early adaptation in evolution. While much is known about how actin filaments grow, mechanisms of their disassembly are incompletely understood. The best-characterized actin disassembly factors are the cofilin family prote...

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Detalles Bibliográficos
Autores principales: Kotila, Tommi, Wioland, Hugo, Enkavi, Giray, Kogan, Konstantin, Vattulainen, Ilpo, Jégou, Antoine, Romet-Lemonne, Guillaume, Lappalainen, Pekka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6876575/
https://www.ncbi.nlm.nih.gov/pubmed/31757941
http://dx.doi.org/10.1038/s41467-019-13213-2