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Dead Cas Systems: Types, Principles, and Applications

The gene editing tool CRISPR-Cas has become the foundation for developing numerous molecular systems used in research and, increasingly, in medical practice. In particular, Cas proteins devoid of nucleolytic activity (dead Cas proteins; dCas) can be used to deliver functional cargo to programmed sit...

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Detalles Bibliográficos
Autores principales: Brezgin, Sergey, Kostyusheva, Anastasiya, Kostyushev, Dmitry, Chulanov, Vladimir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6929090/
https://www.ncbi.nlm.nih.gov/pubmed/31801211
http://dx.doi.org/10.3390/ijms20236041