A Critical Role of PCSK9 in Mediating IL-17-Producing T Cell Responses in Hyperlipidemia

We previously demonstrated that atherogenic Ldlr(−/−)Apobec1(−/−) (LDb) double knockout mice lacking both low-density lipoprotein receptor (LDLR) and apolipoprotein B mRNA-editing catalytic polypeptide-1 (Apobec1) had increased serum IL-17 levels, with T cell programming shifted towards Th17 cells....

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Detalles Bibliográficos
Autores principales: Kim, Young Uk, Kee, Patrick, Danila, Delia, Teng, Ba-Bie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association of Immunologists 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6943168/
https://www.ncbi.nlm.nih.gov/pubmed/31921471
http://dx.doi.org/10.4110/in.2019.19.e41