Mutation-driven epigenetic alterations as a defining hallmark of central cartilaginous tumours, giant cell tumour of bone and chondroblastoma

Recently, specific driver mutations were identified in chondroblastoma, giant cell tumour of bone and central cartilaginous tumours (specifically enchondroma and central chondrosarcoma), sharing the ability to induce genome-wide epigenetic alterations. In chondroblastoma and giant cell tumour of bon...

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Detalles Bibliográficos
Autores principales: Venneker, Sanne, Szuhai, Karoly, Hogendoorn, Pancras C. W., Bovée, Judith V. M. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6968983/
https://www.ncbi.nlm.nih.gov/pubmed/31728625
http://dx.doi.org/10.1007/s00428-019-02699-2