Re‐evaluation of locust bean gum (E 410) as a food additive
Following a request from European Commission, the EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS) provides a scientific opinion re‐evaluating the safety of locust bean gum (E 410) as a food additive. Locust bean gum (E 410) is an authorised food additive in the EU. Locust bean...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7010100/ https://www.ncbi.nlm.nih.gov/pubmed/32625248 http://dx.doi.org/10.2903/j.efsa.2017.4646 |
_version_ | 1783495812411555840 |
---|---|
author | Mortensen, Alicja Aguilar, Fernando Crebelli, Riccardo Di Domenico, Alessandro Frutos, Maria Jose Galtier, Pierre Gott, David Gundert‐Remy, Ursula Lambré, Claude Leblanc, Jean‐Charles Lindtner, Oliver Moldeus, Peter Mosesso, Pasquale Oskarsson, Agneta Parent‐Massin, Dominique Stankovic, Ivan Waalkens‐Berendsen, Ine Woutersen, Rudolf Antonius Wright, Matthew Younes, Maged Brimer, Leon Peters, Paul Wiesner, Jacqueline Christodoulidou, Anna Lodi, Federica Tard, Alexandra Dusemund, Birgit |
author_facet | Mortensen, Alicja Aguilar, Fernando Crebelli, Riccardo Di Domenico, Alessandro Frutos, Maria Jose Galtier, Pierre Gott, David Gundert‐Remy, Ursula Lambré, Claude Leblanc, Jean‐Charles Lindtner, Oliver Moldeus, Peter Mosesso, Pasquale Oskarsson, Agneta Parent‐Massin, Dominique Stankovic, Ivan Waalkens‐Berendsen, Ine Woutersen, Rudolf Antonius Wright, Matthew Younes, Maged Brimer, Leon Peters, Paul Wiesner, Jacqueline Christodoulidou, Anna Lodi, Federica Tard, Alexandra Dusemund, Birgit |
collection | PubMed |
description | Following a request from European Commission, the EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS) provides a scientific opinion re‐evaluating the safety of locust bean gum (E 410) as a food additive. Locust bean gum (E 410) is an authorised food additive in the EU. Locust bean gum (E 410) as specified in the Commission Regulation (EU) No 231/2012 is derived from the ground endosperm of the seeds of the strains of carob tree, Ceratonia siliqua (L.) Taub. (Family Leguminosae). An acceptable daily intake (ADI) ‘not specified’ was allocated by the Joint Food and Agriculture Organization/World Health Organization Expert Committee on Food Additives (JECFA) in 1981. Although not evaluated by the Scientific Committee for Food (SCF), it was accepted by the SCF in 1991 for use in weaning food, and in 1994, in infant formulae for special medical purposes. Locust bean gum is practically undigested, not absorbed intact, but significantly fermented by enteric bacteria in humans. No adverse effects were reported in 90‐day toxicity and carcinogenicity studies in rodents at the highest doses tested and there was no concern with respect to the genotoxicity and to reproductive and developmental toxicity of locust bean gum (E 410). The Panel concluded that there is no need for a numerical ADI for locust bean gum (E 410), and that there is no safety concern for the general population at the refined exposure assessment for its reported uses as a food additive. However, infants and young children consuming foods for special medical purposes may show a higher susceptibility to gastrointestinal effects of locust bean gum due to their underlying medical condition. The Panel concluded that the available data do not allow an adequate assessment of the safety of locust bean gum (E 410) in these foods for infants and young children. |
format | Online Article Text |
id | pubmed-7010100 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-70101002020-07-02 Re‐evaluation of locust bean gum (E 410) as a food additive Mortensen, Alicja Aguilar, Fernando Crebelli, Riccardo Di Domenico, Alessandro Frutos, Maria Jose Galtier, Pierre Gott, David Gundert‐Remy, Ursula Lambré, Claude Leblanc, Jean‐Charles Lindtner, Oliver Moldeus, Peter Mosesso, Pasquale Oskarsson, Agneta Parent‐Massin, Dominique Stankovic, Ivan Waalkens‐Berendsen, Ine Woutersen, Rudolf Antonius Wright, Matthew Younes, Maged Brimer, Leon Peters, Paul Wiesner, Jacqueline Christodoulidou, Anna Lodi, Federica Tard, Alexandra Dusemund, Birgit EFSA J Scientific Opinion Following a request from European Commission, the EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS) provides a scientific opinion re‐evaluating the safety of locust bean gum (E 410) as a food additive. Locust bean gum (E 410) is an authorised food additive in the EU. Locust bean gum (E 410) as specified in the Commission Regulation (EU) No 231/2012 is derived from the ground endosperm of the seeds of the strains of carob tree, Ceratonia siliqua (L.) Taub. (Family Leguminosae). An acceptable daily intake (ADI) ‘not specified’ was allocated by the Joint Food and Agriculture Organization/World Health Organization Expert Committee on Food Additives (JECFA) in 1981. Although not evaluated by the Scientific Committee for Food (SCF), it was accepted by the SCF in 1991 for use in weaning food, and in 1994, in infant formulae for special medical purposes. Locust bean gum is practically undigested, not absorbed intact, but significantly fermented by enteric bacteria in humans. No adverse effects were reported in 90‐day toxicity and carcinogenicity studies in rodents at the highest doses tested and there was no concern with respect to the genotoxicity and to reproductive and developmental toxicity of locust bean gum (E 410). The Panel concluded that there is no need for a numerical ADI for locust bean gum (E 410), and that there is no safety concern for the general population at the refined exposure assessment for its reported uses as a food additive. However, infants and young children consuming foods for special medical purposes may show a higher susceptibility to gastrointestinal effects of locust bean gum due to their underlying medical condition. The Panel concluded that the available data do not allow an adequate assessment of the safety of locust bean gum (E 410) in these foods for infants and young children. John Wiley and Sons Inc. 2017-01-20 /pmc/articles/PMC7010100/ /pubmed/32625248 http://dx.doi.org/10.2903/j.efsa.2017.4646 Text en © 2017 European Food Safety Authority. EFSA Journal published by John Wiley and Sons Ltd on behalf of European Food Safety Authority. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited and no modifications or adaptations are made. |
spellingShingle | Scientific Opinion Mortensen, Alicja Aguilar, Fernando Crebelli, Riccardo Di Domenico, Alessandro Frutos, Maria Jose Galtier, Pierre Gott, David Gundert‐Remy, Ursula Lambré, Claude Leblanc, Jean‐Charles Lindtner, Oliver Moldeus, Peter Mosesso, Pasquale Oskarsson, Agneta Parent‐Massin, Dominique Stankovic, Ivan Waalkens‐Berendsen, Ine Woutersen, Rudolf Antonius Wright, Matthew Younes, Maged Brimer, Leon Peters, Paul Wiesner, Jacqueline Christodoulidou, Anna Lodi, Federica Tard, Alexandra Dusemund, Birgit Re‐evaluation of locust bean gum (E 410) as a food additive |
title | Re‐evaluation of locust bean gum (E 410) as a food additive |
title_full | Re‐evaluation of locust bean gum (E 410) as a food additive |
title_fullStr | Re‐evaluation of locust bean gum (E 410) as a food additive |
title_full_unstemmed | Re‐evaluation of locust bean gum (E 410) as a food additive |
title_short | Re‐evaluation of locust bean gum (E 410) as a food additive |
title_sort | re‐evaluation of locust bean gum (e 410) as a food additive |
topic | Scientific Opinion |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7010100/ https://www.ncbi.nlm.nih.gov/pubmed/32625248 http://dx.doi.org/10.2903/j.efsa.2017.4646 |
work_keys_str_mv | AT reevaluationoflocustbeangume410asafoodadditive AT mortensenalicja reevaluationoflocustbeangume410asafoodadditive AT aguilarfernando reevaluationoflocustbeangume410asafoodadditive AT crebelliriccardo reevaluationoflocustbeangume410asafoodadditive AT didomenicoalessandro reevaluationoflocustbeangume410asafoodadditive AT frutosmariajose reevaluationoflocustbeangume410asafoodadditive AT galtierpierre reevaluationoflocustbeangume410asafoodadditive AT gottdavid reevaluationoflocustbeangume410asafoodadditive AT gundertremyursula reevaluationoflocustbeangume410asafoodadditive AT lambreclaude reevaluationoflocustbeangume410asafoodadditive AT leblancjeancharles reevaluationoflocustbeangume410asafoodadditive AT lindtneroliver reevaluationoflocustbeangume410asafoodadditive AT moldeuspeter reevaluationoflocustbeangume410asafoodadditive AT mosessopasquale reevaluationoflocustbeangume410asafoodadditive AT oskarssonagneta reevaluationoflocustbeangume410asafoodadditive AT parentmassindominique reevaluationoflocustbeangume410asafoodadditive AT stankovicivan reevaluationoflocustbeangume410asafoodadditive AT waalkensberendsenine reevaluationoflocustbeangume410asafoodadditive AT woutersenrudolfantonius reevaluationoflocustbeangume410asafoodadditive AT wrightmatthew reevaluationoflocustbeangume410asafoodadditive AT younesmaged reevaluationoflocustbeangume410asafoodadditive AT brimerleon reevaluationoflocustbeangume410asafoodadditive AT peterspaul reevaluationoflocustbeangume410asafoodadditive AT wiesnerjacqueline reevaluationoflocustbeangume410asafoodadditive AT christodoulidouanna reevaluationoflocustbeangume410asafoodadditive AT lodifederica reevaluationoflocustbeangume410asafoodadditive AT tardalexandra reevaluationoflocustbeangume410asafoodadditive AT dusemundbirgit reevaluationoflocustbeangume410asafoodadditive |