Re‐evaluation of locust bean gum (E 410) as a food additive

Following a request from European Commission, the EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS) provides a scientific opinion re‐evaluating the safety of locust bean gum (E 410) as a food additive. Locust bean gum (E 410) is an authorised food additive in the EU. Locust bean...

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Autores principales: Mortensen, Alicja, Aguilar, Fernando, Crebelli, Riccardo, Di Domenico, Alessandro, Frutos, Maria Jose, Galtier, Pierre, Gott, David, Gundert‐Remy, Ursula, Lambré, Claude, Leblanc, Jean‐Charles, Lindtner, Oliver, Moldeus, Peter, Mosesso, Pasquale, Oskarsson, Agneta, Parent‐Massin, Dominique, Stankovic, Ivan, Waalkens‐Berendsen, Ine, Woutersen, Rudolf Antonius, Wright, Matthew, Younes, Maged, Brimer, Leon, Peters, Paul, Wiesner, Jacqueline, Christodoulidou, Anna, Lodi, Federica, Tard, Alexandra, Dusemund, Birgit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7010100/
https://www.ncbi.nlm.nih.gov/pubmed/32625248
http://dx.doi.org/10.2903/j.efsa.2017.4646
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author Mortensen, Alicja
Aguilar, Fernando
Crebelli, Riccardo
Di Domenico, Alessandro
Frutos, Maria Jose
Galtier, Pierre
Gott, David
Gundert‐Remy, Ursula
Lambré, Claude
Leblanc, Jean‐Charles
Lindtner, Oliver
Moldeus, Peter
Mosesso, Pasquale
Oskarsson, Agneta
Parent‐Massin, Dominique
Stankovic, Ivan
Waalkens‐Berendsen, Ine
Woutersen, Rudolf Antonius
Wright, Matthew
Younes, Maged
Brimer, Leon
Peters, Paul
Wiesner, Jacqueline
Christodoulidou, Anna
Lodi, Federica
Tard, Alexandra
Dusemund, Birgit
author_facet Mortensen, Alicja
Aguilar, Fernando
Crebelli, Riccardo
Di Domenico, Alessandro
Frutos, Maria Jose
Galtier, Pierre
Gott, David
Gundert‐Remy, Ursula
Lambré, Claude
Leblanc, Jean‐Charles
Lindtner, Oliver
Moldeus, Peter
Mosesso, Pasquale
Oskarsson, Agneta
Parent‐Massin, Dominique
Stankovic, Ivan
Waalkens‐Berendsen, Ine
Woutersen, Rudolf Antonius
Wright, Matthew
Younes, Maged
Brimer, Leon
Peters, Paul
Wiesner, Jacqueline
Christodoulidou, Anna
Lodi, Federica
Tard, Alexandra
Dusemund, Birgit
collection PubMed
description Following a request from European Commission, the EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS) provides a scientific opinion re‐evaluating the safety of locust bean gum (E 410) as a food additive. Locust bean gum (E 410) is an authorised food additive in the EU. Locust bean gum (E 410) as specified in the Commission Regulation (EU) No 231/2012 is derived from the ground endosperm of the seeds of the strains of carob tree, Ceratonia siliqua (L.) Taub. (Family Leguminosae). An acceptable daily intake (ADI) ‘not specified’ was allocated by the Joint Food and Agriculture Organization/World Health Organization Expert Committee on Food Additives (JECFA) in 1981. Although not evaluated by the Scientific Committee for Food (SCF), it was accepted by the SCF in 1991 for use in weaning food, and in 1994, in infant formulae for special medical purposes. Locust bean gum is practically undigested, not absorbed intact, but significantly fermented by enteric bacteria in humans. No adverse effects were reported in 90‐day toxicity and carcinogenicity studies in rodents at the highest doses tested and there was no concern with respect to the genotoxicity and to reproductive and developmental toxicity of locust bean gum (E 410). The Panel concluded that there is no need for a numerical ADI for locust bean gum (E 410), and that there is no safety concern for the general population at the refined exposure assessment for its reported uses as a food additive. However, infants and young children consuming foods for special medical purposes may show a higher susceptibility to gastrointestinal effects of locust bean gum due to their underlying medical condition. The Panel concluded that the available data do not allow an adequate assessment of the safety of locust bean gum (E 410) in these foods for infants and young children.
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spelling pubmed-70101002020-07-02 Re‐evaluation of locust bean gum (E 410) as a food additive Mortensen, Alicja Aguilar, Fernando Crebelli, Riccardo Di Domenico, Alessandro Frutos, Maria Jose Galtier, Pierre Gott, David Gundert‐Remy, Ursula Lambré, Claude Leblanc, Jean‐Charles Lindtner, Oliver Moldeus, Peter Mosesso, Pasquale Oskarsson, Agneta Parent‐Massin, Dominique Stankovic, Ivan Waalkens‐Berendsen, Ine Woutersen, Rudolf Antonius Wright, Matthew Younes, Maged Brimer, Leon Peters, Paul Wiesner, Jacqueline Christodoulidou, Anna Lodi, Federica Tard, Alexandra Dusemund, Birgit EFSA J Scientific Opinion Following a request from European Commission, the EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS) provides a scientific opinion re‐evaluating the safety of locust bean gum (E 410) as a food additive. Locust bean gum (E 410) is an authorised food additive in the EU. Locust bean gum (E 410) as specified in the Commission Regulation (EU) No 231/2012 is derived from the ground endosperm of the seeds of the strains of carob tree, Ceratonia siliqua (L.) Taub. (Family Leguminosae). An acceptable daily intake (ADI) ‘not specified’ was allocated by the Joint Food and Agriculture Organization/World Health Organization Expert Committee on Food Additives (JECFA) in 1981. Although not evaluated by the Scientific Committee for Food (SCF), it was accepted by the SCF in 1991 for use in weaning food, and in 1994, in infant formulae for special medical purposes. Locust bean gum is practically undigested, not absorbed intact, but significantly fermented by enteric bacteria in humans. No adverse effects were reported in 90‐day toxicity and carcinogenicity studies in rodents at the highest doses tested and there was no concern with respect to the genotoxicity and to reproductive and developmental toxicity of locust bean gum (E 410). The Panel concluded that there is no need for a numerical ADI for locust bean gum (E 410), and that there is no safety concern for the general population at the refined exposure assessment for its reported uses as a food additive. However, infants and young children consuming foods for special medical purposes may show a higher susceptibility to gastrointestinal effects of locust bean gum due to their underlying medical condition. The Panel concluded that the available data do not allow an adequate assessment of the safety of locust bean gum (E 410) in these foods for infants and young children. John Wiley and Sons Inc. 2017-01-20 /pmc/articles/PMC7010100/ /pubmed/32625248 http://dx.doi.org/10.2903/j.efsa.2017.4646 Text en © 2017 European Food Safety Authority. EFSA Journal published by John Wiley and Sons Ltd on behalf of European Food Safety Authority. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited and no modifications or adaptations are made.
spellingShingle Scientific Opinion
Mortensen, Alicja
Aguilar, Fernando
Crebelli, Riccardo
Di Domenico, Alessandro
Frutos, Maria Jose
Galtier, Pierre
Gott, David
Gundert‐Remy, Ursula
Lambré, Claude
Leblanc, Jean‐Charles
Lindtner, Oliver
Moldeus, Peter
Mosesso, Pasquale
Oskarsson, Agneta
Parent‐Massin, Dominique
Stankovic, Ivan
Waalkens‐Berendsen, Ine
Woutersen, Rudolf Antonius
Wright, Matthew
Younes, Maged
Brimer, Leon
Peters, Paul
Wiesner, Jacqueline
Christodoulidou, Anna
Lodi, Federica
Tard, Alexandra
Dusemund, Birgit
Re‐evaluation of locust bean gum (E 410) as a food additive
title Re‐evaluation of locust bean gum (E 410) as a food additive
title_full Re‐evaluation of locust bean gum (E 410) as a food additive
title_fullStr Re‐evaluation of locust bean gum (E 410) as a food additive
title_full_unstemmed Re‐evaluation of locust bean gum (E 410) as a food additive
title_short Re‐evaluation of locust bean gum (E 410) as a food additive
title_sort re‐evaluation of locust bean gum (e 410) as a food additive
topic Scientific Opinion
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7010100/
https://www.ncbi.nlm.nih.gov/pubmed/32625248
http://dx.doi.org/10.2903/j.efsa.2017.4646
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