Berberine Promotes OATP1B1 Expression and Rosuvastatin Uptake by Inducing Nuclear Translocation of FXR and LXRα

Berberine, a quinoline alkaloid, can be used in combination with statins to enhance hypolipidemic effects and reduce the dose and side effects of statins. The hypolipidemic effects of statins in the liver are mainly regulated by organic anion transporting polypeptides (OATPs), and the expression of...

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Detalles Bibliográficos
Autores principales: Liu, Mingyi, Zhu, Dandan, Wen, Jinhua, Ding, Wei, Huang, Shibo, Xia, Chunhua, Zhang, Hong, Xiong, Yuqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7118773/
https://www.ncbi.nlm.nih.gov/pubmed/32292349
http://dx.doi.org/10.3389/fphar.2020.00375