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Molecular analysis of monoclonal antibodies to group variant capsular polysaccharide of Neisseria meningitidis: recurrent heavy chains and alternative light chain partners

We determined the molecular sequence of monoclonal antibodies (mAbs) to serogroups B and C capsular polysaccharides (PS) of Neisseria meningitidis. N. meningitidis infections are a leading cause of bacterial septicemia and meningitis in humans. Antibodies to PS are fundamental to host defense and di...

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Detalles Bibliográficos
Autores principales: Berry, Jody D., Boese, Darren J., Law, Dennis K.S., Zollinger, Wendell D., Tsang, Raymond S.W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7126428/
https://www.ncbi.nlm.nih.gov/pubmed/15589322
http://dx.doi.org/10.1016/j.molimm.2004.09.002