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Recent insights of T cell receptor-mediated signaling pathways for T cell activation and development

T cell activation requires extracellular stimulatory signals that are mainly mediated by T cell receptor (TCR) complexes. The TCR recognizes antigens on major histocompatibility complex molecules with the cooperation of CD4 or CD8 coreceptors. After recognition, TCR-induced signaling cascades that p...

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Detalles Bibliográficos
Autores principales: Hwang, Jeong-Ryul, Byeon, Yeongseon, Kim, Donghwan, Park, Sung-Gyoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7272404/
https://www.ncbi.nlm.nih.gov/pubmed/32439954
http://dx.doi.org/10.1038/s12276-020-0435-8