Induction of ASC pyroptosis requires gasdermin D or caspase-1/11-dependent mediators and IFNβ from pyroptotic macrophages

Mesenchymal stem cells (MSCs) have been used in cell-based therapies for a variety of disorders. Some factors such as inflammatory mediators in the diseased area might damage the survival of MSCs and affect their efficacy. Pyroptosis is a form of programmed necrosis as a response for immune cells to...

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Detalles Bibliográficos
Autores principales: Zhang, Cuiping, Zhao, Caiqi, Chen, Xiaoyan, Tao, Rujia, Wang, Sijiao, Meng, Guangxun, Liu, Xing, Shao, Changzhou, Su, Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7303158/
https://www.ncbi.nlm.nih.gov/pubmed/32555186
http://dx.doi.org/10.1038/s41419-020-2664-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7303158/
https://www.ncbi.nlm.nih.gov/pubmed/32555186
http://dx.doi.org/10.1038/s41419-020-2664-0

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