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Self-nanoemulsifying System Optimization for Higher Terconazole Solubilization and Non-Irritant Ocular Administration

Purpose: Eye drops’ formulations of poorly water-soluble drugs, offer the advantage of crossing the lipophilic cornea, but their limited aqueous solubility may lead to low ocular bioavailability limiting their therapeutic uses. Terconazole (TZ) is an antifungal drug with low aqueous solubility, rest...

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Detalles Bibliográficos
Autores principales: Yousry, Carol, Zikry, Pakinam Mohsen, Basalious, Emad Basalious, El-Gazayerly, Omaima Naem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tabriz University of Medical Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7335989/
https://www.ncbi.nlm.nih.gov/pubmed/32665897
http://dx.doi.org/10.34172/apb.2020.047