[1,2,4]Triazolo[1,5-a]pyrimidine derivative (Mol-5) is a new NS5-RdRp inhibitor of DENV2 proliferation and DENV2-induced inflammation

Dengue fever is an acute infectious disease caused by dengue virus (DENV) and transmitted by Aedes mosquitoes. There is no effective vaccine or antiviral drug available to date to prevent or treat dengue disease. Recently, RNA-dependent RNA polymerase (RdRp), a class of polymerases involved in the s...

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Detalles Bibliográficos
Autores principales: Wan, Yi-hong, Wu, Wen-yu, Guo, Song-xin, He, Shi-jun, Tang, Xiao-dong, Wu, Xiao-yun, Nandakumar, Kutty Selva, Zou, Min, Li, Lin, Chen, Xiao-guang, Liu, Shu-wen, Yao, Xin-gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471397/
https://www.ncbi.nlm.nih.gov/pubmed/31729469
http://dx.doi.org/10.1038/s41401-019-0316-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471397/
https://www.ncbi.nlm.nih.gov/pubmed/31729469
http://dx.doi.org/10.1038/s41401-019-0316-7

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