New putative insights into neprilysin (NEP)-dependent pharmacotherapeutic role of roflumilast in treating COVID-19

Nowadays, coronavirus disease 2019 (COVID-19) represents the most serious inflammatory respiratory disease worldwide. Despite many proposed therapies, no effective medication has yet been approved. Neutrophils appear to be the key mediator for COVID-19-associated inflammatory immunopathologic, throm...

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Detalles Bibliográficos
Autores principales: El Tabaa, Manar Mohammed, El Tabaa, Maram Mohammed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527794/
https://www.ncbi.nlm.nih.gov/pubmed/33011243
http://dx.doi.org/10.1016/j.ejphar.2020.173615