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Epigenetic activation of the small GTPase TCL contributes to colorectal cancer cell migration and invasion

TC10-like (TCL) is a small GTPase that has been implicated in carcinogenesis. Elevated TCL expression has been observed in many different types of cancers although the underlying epigenetic mechanism is poorly understood. Here we report that TCL up-regulation was associated with high malignancy in b...

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Detalles Bibliográficos
Autores principales: Chen, Baoyu, Fan, Zhiwen, Sun, Lina, Chen, Junliang, Feng, Yifei, Fan, Xiangshan, Xu, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7528090/
https://www.ncbi.nlm.nih.gov/pubmed/32999272
http://dx.doi.org/10.1038/s41389-020-00269-9