STK35 Is Ubiquitinated by NEDD4L and Promotes Glycolysis and Inhibits Apoptosis Through Regulating the AKT Signaling Pathway, Influencing Chemoresistance of Colorectal Cancer

The development of colorectal cancer (CRC) is often sporadic, but its etiology is multifactorial. Chemoresistance of CRC leads to tumor recurrence and poor prognosis in patients. The phosphorylation of protein kinase B (AKT) can activate metabolic reprogramming toward cellular glycolysis. Serine/thr...

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Detalles Bibliográficos
Autores principales: Yang, Haojun, Zhu, Jie, Wang, Guangyao, Liu, Hanyang, Zhou, Yan, Qian, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7578231/
https://www.ncbi.nlm.nih.gov/pubmed/33117809
http://dx.doi.org/10.3389/fcell.2020.582695

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7578231/
https://www.ncbi.nlm.nih.gov/pubmed/33117809
http://dx.doi.org/10.3389/fcell.2020.582695

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