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Hippocampal and cortical tissue-specific epigenetic clocks indicate an increased epigenetic age in a mouse model for Alzheimer’s disease

Epigenetic clocks are based on age-associated changes in DNA methylation of CpG-sites, which can accurately measure chronological age in different species. Recently, several studies have indicated that the difference between chronological and epigenetic age, defined as the age acceleration, could re...

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Detalles Bibliográficos
Autores principales: Coninx, Emma, Chew, Yap Ching, Yang, Xiaojing, Guo, Wei, Coolkens, Amelie, Baatout, Sarah, Moons, Lieve, Verslegers, Mieke, Quintens, Roel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7655172/
https://www.ncbi.nlm.nih.gov/pubmed/33082299
http://dx.doi.org/10.18632/aging.104056