Nanomaterials for Cardiac Tissue Engineering
End stage heart failure is a major cause of death in the US. At present, organ transplant and left-ventricular assist devices remain the only viable treatments for these patients. Cardiac tissue engineering presents the possibility of a new option. Nanomaterials such as gold nanorods (AuNRs) and car...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7664640/ https://www.ncbi.nlm.nih.gov/pubmed/33171802 http://dx.doi.org/10.3390/molecules25215189 |
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author | R. Amin, Devang Sink, Eric Narayan, Suguna P. Abdel-Hafiz, Mostafa Mestroni, Luisa Peña, Brisa |
author_facet | R. Amin, Devang Sink, Eric Narayan, Suguna P. Abdel-Hafiz, Mostafa Mestroni, Luisa Peña, Brisa |
author_sort | R. Amin, Devang |
collection | PubMed |
description | End stage heart failure is a major cause of death in the US. At present, organ transplant and left-ventricular assist devices remain the only viable treatments for these patients. Cardiac tissue engineering presents the possibility of a new option. Nanomaterials such as gold nanorods (AuNRs) and carbon nanotubes (CNTs) present unique properties that are beneficial for cardiac tissue engineering approaches. In particular, these nanomaterials can modulate electrical conductivity, hardness, and roughness of bulk materials to improve tissue functionality. Moreover, they can deliver bioactive cargo to affect cell phenotypes. This review covers recent advances in the use of nanomaterials for cardiac tissue engineering. |
format | Online Article Text |
id | pubmed-7664640 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-76646402020-11-14 Nanomaterials for Cardiac Tissue Engineering R. Amin, Devang Sink, Eric Narayan, Suguna P. Abdel-Hafiz, Mostafa Mestroni, Luisa Peña, Brisa Molecules Review End stage heart failure is a major cause of death in the US. At present, organ transplant and left-ventricular assist devices remain the only viable treatments for these patients. Cardiac tissue engineering presents the possibility of a new option. Nanomaterials such as gold nanorods (AuNRs) and carbon nanotubes (CNTs) present unique properties that are beneficial for cardiac tissue engineering approaches. In particular, these nanomaterials can modulate electrical conductivity, hardness, and roughness of bulk materials to improve tissue functionality. Moreover, they can deliver bioactive cargo to affect cell phenotypes. This review covers recent advances in the use of nanomaterials for cardiac tissue engineering. MDPI 2020-11-07 /pmc/articles/PMC7664640/ /pubmed/33171802 http://dx.doi.org/10.3390/molecules25215189 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review R. Amin, Devang Sink, Eric Narayan, Suguna P. Abdel-Hafiz, Mostafa Mestroni, Luisa Peña, Brisa Nanomaterials for Cardiac Tissue Engineering |
title | Nanomaterials for Cardiac Tissue Engineering |
title_full | Nanomaterials for Cardiac Tissue Engineering |
title_fullStr | Nanomaterials for Cardiac Tissue Engineering |
title_full_unstemmed | Nanomaterials for Cardiac Tissue Engineering |
title_short | Nanomaterials for Cardiac Tissue Engineering |
title_sort | nanomaterials for cardiac tissue engineering |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7664640/ https://www.ncbi.nlm.nih.gov/pubmed/33171802 http://dx.doi.org/10.3390/molecules25215189 |
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