Nanomaterials for Cardiac Tissue Engineering

End stage heart failure is a major cause of death in the US. At present, organ transplant and left-ventricular assist devices remain the only viable treatments for these patients. Cardiac tissue engineering presents the possibility of a new option. Nanomaterials such as gold nanorods (AuNRs) and car...

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Autores principales: R. Amin, Devang, Sink, Eric, Narayan, Suguna P., Abdel-Hafiz, Mostafa, Mestroni, Luisa, Peña, Brisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7664640/
https://www.ncbi.nlm.nih.gov/pubmed/33171802
http://dx.doi.org/10.3390/molecules25215189
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author R. Amin, Devang
Sink, Eric
Narayan, Suguna P.
Abdel-Hafiz, Mostafa
Mestroni, Luisa
Peña, Brisa
author_facet R. Amin, Devang
Sink, Eric
Narayan, Suguna P.
Abdel-Hafiz, Mostafa
Mestroni, Luisa
Peña, Brisa
author_sort R. Amin, Devang
collection PubMed
description End stage heart failure is a major cause of death in the US. At present, organ transplant and left-ventricular assist devices remain the only viable treatments for these patients. Cardiac tissue engineering presents the possibility of a new option. Nanomaterials such as gold nanorods (AuNRs) and carbon nanotubes (CNTs) present unique properties that are beneficial for cardiac tissue engineering approaches. In particular, these nanomaterials can modulate electrical conductivity, hardness, and roughness of bulk materials to improve tissue functionality. Moreover, they can deliver bioactive cargo to affect cell phenotypes. This review covers recent advances in the use of nanomaterials for cardiac tissue engineering.
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spelling pubmed-76646402020-11-14 Nanomaterials for Cardiac Tissue Engineering R. Amin, Devang Sink, Eric Narayan, Suguna P. Abdel-Hafiz, Mostafa Mestroni, Luisa Peña, Brisa Molecules Review End stage heart failure is a major cause of death in the US. At present, organ transplant and left-ventricular assist devices remain the only viable treatments for these patients. Cardiac tissue engineering presents the possibility of a new option. Nanomaterials such as gold nanorods (AuNRs) and carbon nanotubes (CNTs) present unique properties that are beneficial for cardiac tissue engineering approaches. In particular, these nanomaterials can modulate electrical conductivity, hardness, and roughness of bulk materials to improve tissue functionality. Moreover, they can deliver bioactive cargo to affect cell phenotypes. This review covers recent advances in the use of nanomaterials for cardiac tissue engineering. MDPI 2020-11-07 /pmc/articles/PMC7664640/ /pubmed/33171802 http://dx.doi.org/10.3390/molecules25215189 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
R. Amin, Devang
Sink, Eric
Narayan, Suguna P.
Abdel-Hafiz, Mostafa
Mestroni, Luisa
Peña, Brisa
Nanomaterials for Cardiac Tissue Engineering
title Nanomaterials for Cardiac Tissue Engineering
title_full Nanomaterials for Cardiac Tissue Engineering
title_fullStr Nanomaterials for Cardiac Tissue Engineering
title_full_unstemmed Nanomaterials for Cardiac Tissue Engineering
title_short Nanomaterials for Cardiac Tissue Engineering
title_sort nanomaterials for cardiac tissue engineering
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7664640/
https://www.ncbi.nlm.nih.gov/pubmed/33171802
http://dx.doi.org/10.3390/molecules25215189
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