AdipoR1/AdipoR2 dual agonist recovers nonalcoholic steatohepatitis and related fibrosis via endoplasmic reticulum-mitochondria axis

Chronic nonalcoholic steatohepatitis (NASH) is a metabolic disorder that often leads to liver fibrosis, a condition with limited therapy options. Adiponectin is an adipocytokine that regulates glucose and lipid metabolism via binding to its receptors AdipoR1 and AdipoR2, and AdipoRs signaling is rep...

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Detalles Bibliográficos
Autores principales: Xu, Hongjiao, Zhao, Qian, Song, Nazi, Yan, Zhibin, Lin, Runfeng, Wu, Shuohan, Jiang, Lili, Hong, Sihua, Xie, Junqiu, Zhou, Huihao, Wang, Rui, Jiang, Xianxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7669869/
https://www.ncbi.nlm.nih.gov/pubmed/33199780
http://dx.doi.org/10.1038/s41467-020-19668-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7669869/
https://www.ncbi.nlm.nih.gov/pubmed/33199780
http://dx.doi.org/10.1038/s41467-020-19668-y

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