4-Methylcytosine DNA modification is critical for global epigenetic regulation and virulence in the human pathogen Leptospira interrogans

In bacteria, DNA methylation can be facilitated by ‘orphan’ DNA methyltransferases lacking cognate restriction endonucleases, but whether and how these enzymes control key cellular processes are poorly understood. The effects of a specific modification, 4-methylcytosine (4mC), are even less clear, a...

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Detalles Bibliográficos
Autores principales: Gaultney, Robert A, Vincent, Antony T, Lorioux, Céline, Coppée, Jean-Yves, Sismeiro, Odile, Varet, Hugo, Legendre, Rachel, Cockram, Charlotte A, Veyrier, Frédéric J, Picardeau, Mathieu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708080/
https://www.ncbi.nlm.nih.gov/pubmed/33301041
http://dx.doi.org/10.1093/nar/gkaa966

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708080/
https://www.ncbi.nlm.nih.gov/pubmed/33301041
http://dx.doi.org/10.1093/nar/gkaa966

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