The Impact of Halogenated Phenylalanine Derivatives on NFGAIL Amyloid Formation

The hexapeptide hIAPP(22–27) (NFGAIL) is known as a crucial amyloid core sequence of the human islet amyloid polypeptide (hIAPP) whose aggregates can be used to better understand the wild‐type hIAPP′s toxicity to β‐cell death. In amyloid research, the role of hydrophobic and aromatic‐aromatic intera...

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Detalles Bibliográficos
Autores principales: Chowdhary, Suvrat, Moschner, Johann, Mikolajczak, Dorian J., Becker, Maximilian, Thünemann, Andreas F., Kästner, Claudia, Klemczak, Damian, Stegemann, Anne‐Katrin, Böttcher, Christoph, Metrangolo, Pierangelo, Netz, Roland R., Koksch, Beate
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7756607/
https://www.ncbi.nlm.nih.gov/pubmed/33405360
http://dx.doi.org/10.1002/cbic.202000373