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Development and characterisation of SMURF2-targeting modifiers

The C2-WW-HECT-domain E3 ubiquitin ligase SMURF2 emerges as an important regulator of diverse cellular processes. To date, SMURF2-specific modulators were not developed. Here, we generated and investigated a set of SMURF2-targeting synthetic peptides and peptidomimetics designed to stimulate SMURF2’...

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Detalles Bibliográficos
Autores principales: Manikoth Ayyathan, Dhanoop, Levy-Cohen, Gal, Shubely, Moran, Boutros-Suleiman, Sandy, Lepechkin-Zilbermintz, Veronica, Shokhen, Michael, Albeck, Amnon, Gruzman, Arie, Blank, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7808752/
https://www.ncbi.nlm.nih.gov/pubmed/33430646
http://dx.doi.org/10.1080/14756366.2020.1871337