Azacitidine regulates DNA methylation of GADD45γ in myelodysplastic syndromes

BACKGROUND: Myelodysplastic syndrome (MDS) is a heterogeneous clonal disease originated from hematopoietic stem cells. Epigenetic studies had demonstrated that DNA methylation and histone acetylation were abnormal in MDS. Azacitidine is an effective drug in the treatment of demethylation. METHODS: R...

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Detalles Bibliográficos
Autores principales: Yang, Yanli, Li, Jun, Geng, Yinghua, Liu, Lin, Li, Dianming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7891504/
https://www.ncbi.nlm.nih.gov/pubmed/33080073
http://dx.doi.org/10.1002/jcla.23597

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7891504/
https://www.ncbi.nlm.nih.gov/pubmed/33080073
http://dx.doi.org/10.1002/jcla.23597

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