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CXCL9-expressing tumor-associated macrophages: new players in the fight against cancer

Tumor-associated macrophages (TAMs) are among the main contributors to immune suppression in the tumor microenvironment, however, TAM depletion strategies have yielded little clinical benefit. Here, we discuss the concept that TAMs are also key regulators of anti-PD(L)-1-mediated CD8 T cell-dependen...

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Detalles Bibliográficos
Autores principales: Marcovecchio, Paola Marie, Thomas, Graham, Salek-Ardakani, Shahram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7919587/
https://www.ncbi.nlm.nih.gov/pubmed/33637602
http://dx.doi.org/10.1136/jitc-2020-002045