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G protein βγ translocation to the Golgi apparatus activates MAPK via p110γ-p101 heterodimers

The Golgi apparatus (GA) is a cellular organelle that plays a critical role in the processing of proteins for secretion. Activation of G protein–coupled receptors at the plasma membrane (PM) induces the translocation of G protein βγ dimers to the GA. However, the functional significance of this tran...

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Detalles Bibliográficos
Autores principales: Khater, Mostafa, Wei, Zhe, Xu, Xin, Huang, Wei, Lokeshwar, Bal L., Lambert, Nevin A., Wu, Guangyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7949113/
https://www.ncbi.nlm.nih.gov/pubmed/33493514
http://dx.doi.org/10.1016/j.jbc.2021.100325