EVI1 dysregulation: impact on biology and therapy of myeloid malignancies

Ecotropic viral integration site 1 (Evi1) was discovered in 1988 as a common site of ecotropic viral integration resulting in myeloid malignancies in mice. EVI1 is an oncogenic zinc-finger transcription factor whose overexpression contributes to disease progression and an aggressive phenotype, corre...

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Detalles Bibliográficos
Autores principales: Birdwell, Christine, Fiskus, Warren, Kadia, Tapan M., DiNardo, Courtney D., Mill, Christopher P., Bhalla, Kapil N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7985498/
https://www.ncbi.nlm.nih.gov/pubmed/33753715
http://dx.doi.org/10.1038/s41408-021-00457-9