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Inhibiting Monoacylglycerol Lipase Suppresses RANKL-Induced Osteoclastogenesis and Alleviates Ovariectomy-Induced Bone Loss

Osteoporosis is a common chronic metabolic bone disease characterized by reduced trabecular bone and increased bone fragility. Monoacylglycerol lipase (MAGL) is a lipolytic enzyme to catalyze the hydrolysis of monoglycerides and specifically degrades the 2-arachidonoyl glycerol (2-AG). Previous stud...

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Detalles Bibliográficos
Autores principales: Liu, Hui, Zhou, Chuankun, Qi, Dahu, Gao, Yutong, Zhu, Meipeng, Tao, Tenghui, Sun, Xuying, Xiao, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7994615/
https://www.ncbi.nlm.nih.gov/pubmed/33777947
http://dx.doi.org/10.3389/fcell.2021.640867