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The Warburg Effect Occurs Rapidly in Stimulated Human Adult but Not Umbilical Cord Blood Derived Macrophages

The Warburg effect, defined as increased glycolysis and decreased oxidative phosphorylation, occurs in murine macrophages following LPS stimulation and is required for activation. There are differences between human and murine macrophage metabolic responses to stimulation, with peak metabolite conce...

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Detalles Bibliográficos
Autores principales: Ó Maoldomhnaigh, Cilian, Cox, Donal J., Phelan, James J., Malone, Fergal D., Keane, Joseph, Basdeo, Sharee A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8076563/
https://www.ncbi.nlm.nih.gov/pubmed/33927724
http://dx.doi.org/10.3389/fimmu.2021.657261