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Macrophage migration inhibitory factor regulates joint capsule fibrosis by promoting TGF-β1 production in fibroblasts

Joint capsule fibrosis caused by excessive inflammation results in post-traumatic joint contracture (PTJC). Transforming growth factor (TGF)-β1 plays a key role in PTJC by regulating fibroblast functions, however, cytokine-induced TGF-β1 expression in specific cell types remains poorly characterized...

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Detalles Bibliográficos
Autores principales: Zhang, Yuxin, Liu, Zhonglong, Wang, Kexin, Lu, Shenji, Fan, Shuai, Xu, Lili, Cai, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8120472/
https://www.ncbi.nlm.nih.gov/pubmed/33994866
http://dx.doi.org/10.7150/ijbs.57025