Pharmacogenetic Associations Between Atazanavir/UGT1A1*28 and Efavirenz/rs3745274 (CYP2B6) Account for Specific Adverse Reactions in Chilean Patients Undergoing Antiretroviral Therapy

Background: Efavirenz (EFV), a non-nucleoside reverse transcriptase inhibitor, and atazanavir (ATV), a protease inhibitor, are drugs widely used in antiretroviral therapy (ART) for people living with HIV. These drugs have shown high interindividual variability in adverse drug reactions (ADRs). UGT1A...

Descripción completa

Detalles Bibliográficos
Autores principales: Poblete, Daniela, Bernal, Fernando, Llull, Gabriel, Archiles, Sebastian, Vasquez, Patricia, Chanqueo, Leonardo, Soto, Nicole, Lavanderos, María A., Quiñones, Luis A., Varela, Nelson M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8170096/
https://www.ncbi.nlm.nih.gov/pubmed/34093191
http://dx.doi.org/10.3389/fphar.2021.660965

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8170096/
https://www.ncbi.nlm.nih.gov/pubmed/34093191
http://dx.doi.org/10.3389/fphar.2021.660965

Ejemplares similares