Genetic Modeling of the Neurodegenerative Disease Spinocerebellar Ataxia Type 1 in Zebrafish

Dominant spinocerebellar ataxias (SCAs) are progredient neurodegenerative diseases commonly affecting the survival of Purkinje cells (PCs) in the human cerebellum. Spinocerebellar ataxia type 1 (SCA1) is caused by the mutated ataxin1 (Atx1) gene product, in which a polyglutamine stretch encoded by C...

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Detalles Bibliográficos
Autores principales: Elsaey, Mohamed A., Namikawa, Kazuhiko, Köster, Reinhard W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8306488/
https://www.ncbi.nlm.nih.gov/pubmed/34298970
http://dx.doi.org/10.3390/ijms22147351

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8306488/
https://www.ncbi.nlm.nih.gov/pubmed/34298970
http://dx.doi.org/10.3390/ijms22147351

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