Programmable System of Cas13-Mediated RNA Modification and Its Biological and Biomedical Applications

Clustered regularly interspaced short palindromic repeats (CRISPR)-Cas13 has drawn broad interest to control gene expression and cell fate at the RNA level in general. Apart from RNA interference mediated by its endonuclease activity, the nuclease-deactivated form of Cas13 further provides a versati...

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Detalles Bibliográficos
Autores principales: Tang, Tian, Han, Yingli, Wang, Yuran, Huang, He, Qian, Pengxu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8353156/
https://www.ncbi.nlm.nih.gov/pubmed/34386490
http://dx.doi.org/10.3389/fcell.2021.677587