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USP14 maintains HIF1-α stabilization via its deubiquitination activity in hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is the most common visceral neoplasms with its heterogeneity and high rate of recurrence. HCC is characterized to be delayed diagnosis and the development of resistant disease. However, the molecular mechanism for HCC pathogenesis and progression remains largely unknow...

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Detalles Bibliográficos
Autores principales: Lv, Chi, Wang, Shengli, Lin, Lin, Wang, Chunyu, Zeng, Kai, Meng, Yiming, Sun, Ge, Wei, Shan, Liu, Yefu, Zhao, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8380251/
https://www.ncbi.nlm.nih.gov/pubmed/34420039
http://dx.doi.org/10.1038/s41419-021-04089-6