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USP14 maintains HIF1-α stabilization via its deubiquitination activity in hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is the most common visceral neoplasms with its heterogeneity and high rate of recurrence. HCC is characterized to be delayed diagnosis and the development of resistant disease. However, the molecular mechanism for HCC pathogenesis and progression remains largely unknow...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8380251/ https://www.ncbi.nlm.nih.gov/pubmed/34420039 http://dx.doi.org/10.1038/s41419-021-04089-6 |