Carcinoembryonic antigen as a specific glycoprotein ligand of rBC2LCN lectin on pancreatic ductal adenocarcinoma cells

The rBC2LCN lectin, known as a stem cell marker probe that binds to an H type 3 fucosylated trisaccharide motif, was recently revealed to also bind to pancreatic ductal adenocarcinoma (PDAC) cells. A lectin‐drug conjugate was generated by fusing rBC2LCN with a cytocidal toxin, and it showed a strong...

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Detalles Bibliográficos
Autores principales: Furuta, Tomoaki, Oda, Tatsuya, Kiyoi, Kayo, Yusuke, Ozawa, Kimura, Sota, Kurimori, Ko, Miyazaki, Yoshihiro, Yu, Yang, Furuya, Kinji, Akashi, Yoshimasa, Shimomura, Osamu, Tateno, Hiroaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8409409/
https://www.ncbi.nlm.nih.gov/pubmed/34115906
http://dx.doi.org/10.1111/cas.15023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8409409/
https://www.ncbi.nlm.nih.gov/pubmed/34115906
http://dx.doi.org/10.1111/cas.15023

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