Novel Nitrogen-Based Chalcone Analogs Provoke Substantial Apoptosis in HER2-Positive Human Breast Cancer Cells via JNK and ERK1/ERK2 Signaling Pathways

Natural chalcones possess antitumor properties and play a role as inducers of apoptosis, antioxidants and cytotoxic compounds. We recently reported that novel nitrogen chalcone-based compounds, which were generated in our lab, have specific effects on triple-negative breast cancer cells. However, th...

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Detalles Bibliográficos
Autores principales: Rizeq, Balsam, Gupta, Ishita, Kheraldine, Hadeel, Elkhalifa, Dana, Al-Farsi, Halema F., Moustafa, Ala-Eddin Al, Khalil, Ashraf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431802/
https://www.ncbi.nlm.nih.gov/pubmed/34502529
http://dx.doi.org/10.3390/ijms22179621

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431802/
https://www.ncbi.nlm.nih.gov/pubmed/34502529
http://dx.doi.org/10.3390/ijms22179621

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